Following the Industry 4.0 vision of a full digitization of the industry, time-critical services and applications, allowing network infrastructures to deliver information with determinism and reliability, are becoming more and more relevant for a set of vertical sectors.

Background: Cancer is an extremely heterogeneous disease, both intra and inter cancer types.

While studies have established the existence of differences in the epidemiological and clinical patterns of lung adenocarcinoma between male and female patients, we know relatively little regarding the molecular mechanisms underlying such sex-based differences.